1. 2nd Annual Alpha Project Research Symposium - Aims to highlight progress in creating a quantitative model of a biological information-processing pathway: the yeast pheromone signal transduction pathway. University of California, Berkeley. 2. Hedgehog Signaling Pathway - Guide to bioinformatic resources and annotations from San Francisco State University. 3. Protein Kinase Resource - Compendium of information on the protein kinase family of enzymes. 4. AfCS-Nature Signaling Gateway - Joint resource from Alliance for Cellular Signaling, featuring meetings, workshops, primary research papers, reviews, database of molecules and protein data, updated in Durham, NC and editorial office at Nature Publishing Group, London, UK. Full access requires registration. 5. Anderson Laboratory NEW! - Research on adiposomes, cholestrerol regulation, receptor clustering, and mechanisms of caveolae membrane traffic. Includes image gallery, links to publications, and profiles of staff at University of Texas Southwestern Medical Center at Dallas. 6. Cardiovascular Research Institute NEW! - Studies on regulation of cell polarity during chemotaxis, using combination of biochemical techniques, reverse genetics and live imaging to dissect the feedback circuits. Includes history and programs at University of California, San Francisco. 7. Cell Intelligence - Experimental research over two decades into the question of whether cells have a central signal integration system, including author profile, at Northwestern University, Evanston, IL. 8. Cell Signaling Pathways NEW! - Educational resource to browse or download powerpoint slides, on apoptosis, cell cycle, cytokines, growth factors, gene regulation, ion channels, neurotransmission, and the role of nitric oxide. Links to technical support and customer services of Sigma-Aldrich Co. 9. Cell Signaling Technology, Inc. - Phospho-specific Antibodies and other Innovative Discovery Tools for Cell Signaling Research. 10. Cell Signalling - Research focused on phosphoinositide 3-kinases, in lipid phosporylation within cell membranes. Phospholipids initiate cascades for cellular activities. Related links to groups at the Ludwig Institute for Cancer Research, London, UK. 11. Chris Parsons - Hobbies, interests and academic work on the physiological, pathological and neurotransmitter roles of glutamate in the central nervous system. Includes publications in PDF, guest-book of English scientist working in Frankfurt, Germany. 12. Cyclic GMP - Overview of the receptor interaction and intracellular pathway, focusing on the role of nitric oxide, and their clinical relevance. Includes diagrams, animations, links to related pages and free access publications. 13. Drastic - Database resource for analysis of signal transduction in cells;, a project identifying plant genes regulated in response to infection or other stresses. 14. Dynamic Signaling Maps - Web-based software for creating, editing, annotating, and storing biological signaling pathways, doing consistency checks when integrating data from multiple sources, producing biomolecular network maps, and integrating pathways with protein-protein interaction data. 15. Fenteany Research Group - Projects, links to publications, related resources, contacts for researchers at the University of Illinois at Chicago. 16. Field Laboratory NEW! - Studies on signal transduction by phosphoinositides in mammalian cells. Includes research, publications, photosd of personnel, related links and location at University of California, San Diego. 17. Ion Channels and Thyroid Hormones - Research in the modulation of synaptic function by hormones and their non-genomic action in the amphibian neuromuscular junction, at the Department of Physiology, UCC, Bayamón, PR. 18. KEGG - KEGG Regulatory Pathways -- a collection of graphical pathway maps, ortholog group tables, and molecular catalogs. Contains a few signaling pathway maps related to medical conditions. 19. Levin and Buck Lab - Research on bicarbonate regulation of second messenger cAMP pathway, publications, related links and staff contacts at Department of Pharmacology, Weill Medical College of Cornell University, New York City. 20. Mammalian MAPK Signalling Pathways - Signaling related to the mitogen-activated protein kinase pathway, with links to SAPK and p38, and related sequennces, from Ontario Cancer Institute, Toronto, Canada. 21. Publicover Research Group, - Signaling studies in human bone cell and sperm, before fertilization at University of Birmingham, UK. 22. Receptors, Signaling and Proteomics - Research on growth factor transforming and GPI-linked receptors, with links to relevant references. Includes profiles of group members at NRC Biotechnology Research Institute, Canada. 23. Redox Signaling - Overview the role of free radicals and other electronically-activated as cellular messengers, and its relevance to human disease conditions in stroke and alopecia. 24. SenseLab - International network of researchers developing comprehensive multidisciplinary models of neurons and neural systems, using the olfactory receptors pathway as a model, arranged as six databases, maintained at Yale University. 25. Signal Transduction in the Nervous System - Signal Transduction Laboratory at East Carolina University Brody School of Medicine. Research focuses on signaling pathways activated in the nervous system during development, disease and aging. 26. Signal Transduction Knowledge Environment - Resources in the field offered by Science Online. Requires registration, and subscription fee for most content. 27. SPAD: Signaling Pathway Database - Diagrams of pathways, linking to sequences of growth factors, cytokines and hormones, and to their genetic information. Part of project at the Graduate School of Genetic Resources Technology, Kyushu University, Japan. 28. The Holmgren Lab - Research focused on the Hedgehog (Hh) signaling pathway, in development of invertebrate and vertebrate appendages, and differentiation in the fruit fly. Includes glossary with information on other pathways, publications linked to NML, staff photos and contacts at Northwestern University, Evanston, IL. 29. The Nuclear Receptor Resource - A collection of databases devoted to nuclear receptors, such as steroid receptors. 30. Upstate Cell Signalling Symposium - Details of meeting on regulation and therapeutic potential of the phosphoinositol 3-kinase PKB signaling pathway, for four days in Dundee, Scotland. 31. WWW Virtual Library: Signal Transduction - Annotated index of online resources dealing with sub-cellular messaging in cell growth, differentiation and stimulus response.

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