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1. |
A TV Show on RNAi by PBS
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NOVA scienceNOW TV program describes RNAi as a major breakthrough in gene therapy with enormous medical promise. Provides basic overview of RNAi technology, current therapeutic approaches, and interview with the experts in the field. Includes 15-minutes TV broadcast segment on RNAi.
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2. |
Article on RNAi by GNN
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Online article describing gene silencing mechanism and how RNAi can be used for HIV treatment.
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3. |
Article on RNAi by HOPES
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Online article describes basic mechanism of RNAi and how it can be applied for Huntington's disease treatment.
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4. |
Drosophila RNAi Resource
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Informational RNAi resource on studying drosophila genes and their roles in development by Society for Developmental Biology.
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5. |
Gene Silencing Mechanism
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Animation of post transcriptional gene silencing or RNA Interference (RNAi) by Nature Reviews Genetics.
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6. |
Isis Pharmaceuticals Inc.
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Discovers and develops drugs based upon antisense and RNAi technology. Focused on RNA as a therapeutic target. Includes overview of recent research and drug development approaches.
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7. |
Navigating Journey of Genome to Medicine
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Review article on RNAi by International Herald Tribune. Provides an overview on RNA Interference discovery, current research efforts, and therapeutic potential.
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8. |
Oligonucleotide Therapeutic Society
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Society host conferences on academia and industry-based research and development of oligonucleotide therapeutics: RNAi, antisense, and others. Provides society overview, publication materials, meetings, and contact information.
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9. |
Protein Lounge
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Provides database that contains targets against mRNA sequences throughout a variety of organisms. Includes gene search option, and disease-specific siRNA genes.
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10. |
RNAi Database
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Contains all siRNA from C. elegans including assay, resulting phenotypes, dsRNA target location. Database provides Gene/Protein or Phenotype search options.
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11. |
RNAi News
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Online resource for scientists, researchers, technologists, and executives engaged in RNA Interference, functional genomics, and drug discovery. Offers industry news, product reviews, and meetings information.
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RNAi Research and Therapeutics Conference
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Meeting organized by GTCbio with main focus on RNA Interference. Purpose of the conference is to facilitate the exchange of biopharmaceutical and biomedical intelligence between industry leaders, academic and government organizations, and the financial community. Provides meeting agenda, poster session and registration information.
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13. |
RNAi Resource at Macalester College
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Informational resource, including RNAi mechanism, overview of current studies, and related research protocols.
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14. |
RNAi Therapies by Nature Medicine Journal
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Article on RNAi therapy potential describing advantages for novel drug discovery and safety concerns.
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15. |
RNAi.net
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Online resource offering information RNA interference and related issues: news, interviews, articles, techniques.
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16. |
RNAi@elegansNet
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Directory on gene silencing by RNA interference (RNAi) literature and resources.
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17. |
The RNAi Web
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Online resource for RNA Interference (RNAi) technology. Offers overview of technology, references, and links on other RNAi-related web resources.
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18. |
Article on siRNA from NodeWorks Encyclopedia
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Describes small interfering RNA (siRNA) function, structure, use in research, and potential application for therapy.
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19. |
Cambridge Healthtech Institute
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CHI organizes RNAi-related conferences throughout the US and Europe, including therapeutics, pharmaceutics, drug development, target discovery, and biodefense. Provides biotechnology news and conferences information.
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20. |
Cenix BioScience GmbH
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Develops RNA-mediated Interference (RNAi) technology for the discovery of conventional therapeutics. Biological research data and company information is provided.
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21. |
Focus Areas: RNAi from Invitrogen
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Educational and product support page. Includes RNAi overview, history, and research suggestions for gene silencing experiments.
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22. |
Induction of an interferon response by RNAi vectors in mammalian cells
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Article from journal Nature Genetics about potential complications of use of RNAi vector-based technology for therapeutics.
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23. |
InFocus RNAi Web Broadcast by Bio.com
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RNAi Advances In 2005: Technologies And Applications. Bio.com provides an online RNAi technology-focused webcast, experts in the field discuss new insights into the regulation of gene expression by RNAi. Includes event description and downloadable webcast.
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24. |
Journal of RNAi and Gene Silencing
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Publishes peer-reviewed articles addressing the biology and application of RNA interference and gene silencing. Includes information about journal aims and scope, publication policies, and manuscript submission. Provides online access to journal articles.
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25. |
NodeWorks Encyclopedia Article on RNAi
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Online article describing the basics of RNA Interference (RNAi) mechanism.
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26. |
Oligoengine
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Oligonucleotide design software for applications such as RNAi, DNA methylation, antisense, and genome arrays.
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27. |
Ordway Research Institute
NEW!
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Not-for-profit corporation with a mission to translate basic science observations into therapeutics. Provides research services including quantitation of endogenous levels of microRNAs and mRNAs from experimental samples. Includes information on research focus areas and technology development.
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28. |
Pharmaceutical Discovery
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Peer-review online journal publishing articles on recent advances in life sciences research and drug discovery. Includes RNAi related news, overview of new technology, and research articles.
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29. |
RNA Interference
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Interactive online resource from Howard Hughes Medical Institute. Presents RNAi mechanism and overview of key scientific findings.
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30. |
RNA Interference at Journal Nature
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Focus RNA Interference - online resource publishing recent advances in RNAi field, and novel applications in Nature Cell Biology and Nature Reviews.
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31. |
RNAi BioForum
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Online forum for siRNA, microRNA and RNAi methods discussion.
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32. |
RNAi Gateway
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Web resource from BioMed Central. Provides RNA Interference (RNAi) research highlights, journal links, news, and meeting information.
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33. |
RNAi Mechanism Animation by Journal Nature
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An animation from Nature Publishing Group on the mechanism of RNA Interference (RNAi).
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34. |
RNAi Meeting at Cold Spring Harbor Laboratory
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Conference on RNA Interference (RNAi) and eukaryotic mRNA processing. Meeting focus on the mechanisms and regulation of RNA interference and related mechanisms. Provides information regarding meeting registration, program, and discussion topics.
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35. |
RNAi Meeting: From Target Discovery and Validation to Therapeutic Development
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CHI's Discovery on Target RNAi meeting organized by Cambridge Healthtech Institute at Boston, Massachusetts, October 25-26, 2006. Meeting provides overview of various aspects in RNA Interference (RNAi) research, ranging from in vitro and in vivo drug discovery research to therapeutic applications. Online meeting information is available: plenary sessions, exhibits, and poster presentations.
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36. |
RNAi Resource at Ambion
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Online RNA Interference (RNAi) resource. Provide scientific and technical support, information on microRNA and small interfering RNA application in gene expression research.
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37. |
RNAi Therapeutics: How Likely, How Soon?
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Review article from PLoS Biology journal. Describes mechanism of RNA Interference, potential applications towards therapeutics, and current problems associated with delivery.
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38. |
RNAi Transfection Resource
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Review of transfection techniques such as electroporation, denrimers and lipids that are used for transfection of DNA, RNA, and siRNA. Includes information on optimized cell type specific transfection systems.
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39. |
Rosetta Genomics
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Israel-based microRNA genomics company, develops bioinformatic tools for miRNA gene detection approach.
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40. |
SBS Conference
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The Society for Biomolecular Screening holds a conference on high-throughput RNAi screening approach using siRNA/shRNA libraries on September 11-15, 2005.
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41. |
Second Annual Meeting of the Oligonucleotide Therapeutics Society
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Yearly conference organized by New York Academy of Sciences. Scientists from industry and academia meet to discuss use of oligonucleotide-based gene-silencing techniques for development of innovative therapeutics. Includes information about conference registration, preliminary program, and abstract submission.
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42. |
SI RNA - Small Interference RNA Resources
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Online resource from Ion Channel Media Group. Provides news, publication links, and citations of the recent literature relevant to RNA Interference research.
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43. |
TargetScan
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Online software provided by MIT for prediction of microRNA targets. Provides research data and online software for microRNA target identification and analysis.
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44. |
The microRNA Registry
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Online resource provides a service for the assignment of miRNA gene names. Provides searchable database of published miRNA sequences. Includes data and research application information.
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45. |
The RNAi vs. HIV
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Reviews the use of this therapy in fighting HIV. Includes mechanism, difficulties, terms, and featured experiments.
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46. |
Transcriptional Gene Silencing
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Mechanisms of TGS by Kevin Morris laboratory. Includes description of HIV research performed using lentiviral vector gene therapy and RNAi mediated gene silencing.
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