Alpha-1 results in low levels or a lack of an essential blood protein that protects tissues in the lungs from being destroyed by enzymes released from the body's own white blood cells. 1. Alpha-1 Antitrypsin Deficiency Association - Non-profit organization offering information and support to patients, caregivers, and families effected by this disease. 2. Pediatric Oncall - Offers a description of alpha–l antitrypsin, including the affects on the liver and how it presents. 3. Alpha 1 Awareness Alliance - A site where members of the medical professions and the public can find information about alpha 1-antitrypsin- deficiency. Includes news, reports and links. 4. Alpha-1 Advocacy Alliance - Offers information about this disorder, resources for medical support, advocacy, public policy, health tips, and free membership. 5. Alpha-1 Community - Members can submit news, events, photos or any information relating to the disorder. Requires free registration. 6. Canadian Liver Foundation: Alpha-1 Antitrypsin Deficiency - Reviews the cause, symptoms, risk of lung and liver disease, and treatment. 7. Late Manifestation of Alpha-1-antitrypsin Deficiency in the Adult - Literature review of late manifestations including hepatic decompensation and hepatocellular cancer in alpha-1-antitrypsin deficiency. 8. MedicineNet - An Alpha-1 antitrypsin deficiency article with details such as what it is, normal lungs and how they work, smoking, risk factors, how it is inherited, signs, symptoms and treatment. 9. Merck Manual: Alpha1-Antitrypsin Deficiency1 - Offers information including description, symptoms, diagnosis, and treatment. Explains what alpha1-antitrypsin is and why it is important. 10. Patient UK - A list of resources and support for persons living in the UK who are interested in Alpha-1 Antitrypsin Deficiency. 11. Spiderspun - A haven for those affected by Alpha-1 Antirypsin Deficiency. Facts, chat rooms, assistance programs, and reference material. 12. Understanding Alpha-1 Antitrypsin Deficiency - Information on signs and symptoms of this disorder, as well as risk factors and treatment. 13. University of Cambridge - Laboratory in Cambridge, UK, researching the cause and treatment of alpha1-antitrypsin deficiency.

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